CD45/PTPRC, His, Human

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
GSC-Z05136-100	100 µg		-		Request delivery time estimate		524.00€
GSC-Z05136-500	500 µg		-		Request delivery time estimate		1,761.00€

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PTPRC (also known as CD45),T cells require the protein tyrosine phosphatase CD45 to detect and... more

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Product information "CD45/PTPRC, His, Human"

PTPRC (also known as CD45),T cells require the protein tyrosine phosphatase CD45 to detect and respond to antigen because it activates the Src family kinase Lck, which phosphorylates the T cell antigen receptor (TCR) complex. CD45 ativates Lck by opposing the negative regulatory kinase Csk. Paradoxically, CD45 has also been implicated in suppressing TCR signaling by dephosphorylating the same signaling motifs within the TCR complex upon which Lck acts.

Keywords:	T200, PTPRC, Leukocyte common antigen, Receptor-type tyrosine-protein phosphatase C
Supplier:	GenScript
Supplier-Nr:	Z05136

Properties

Conjugate:	No
Species reactivity:	human
MW:	61.9 kD
Purity:	>95% (Bis-Tris PAGE)

Database Information

KEGG ID :	K06478 \| Matching products
UniProt ID :	P08575 \| Matching products
Gene ID :	GeneID 5788 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+4°C (International: °C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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