CD275 [B7-H2] (human):Fc (mouse) (rec.)

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
CHI-HF-211B7H2-C100	100 µg		-	-	3 - 9 business days*		429.00€

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Human B7-H2 is a member of the growing B7 family of immune costimulatory proteins. Other family... more

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Product information "CD275 [B7-H2] (human):Fc (mouse) (rec.)"

Human B7-H2 is a member of the growing B7 family of immune costimulatory proteins. Other family members include B7-1, B7-2, B7-H1 (PD-L1), PD-L2 and B7-H3. B7 proteins are members of the immunoglobulin (Ig) superfamily, the extracellular domains contain 2 Ig-like domains and all members have short cytoplasmic domains. B7-H2 has been identified as the ligand for ICOS, a member of the CD28 family of costimulatory receptors. Human B7-H2 is expressed constitutively on resting B cells, dendritic cells and at low levels on monocytes. The B7-H2/ICOS interaction appears to play roles in T cell dependent B cell activation and Th differentiation.

Keywords:	B7H2, B7-H2, CD275, B7RP-1, ICOSLG, ICOS ligand, B7 homolog 2, B7-related protein 1, B7-like protein Gl50, B7-H2, ICOS Ligand, B7-like Protein Gl50, B7RP-1
Supplier:	Chimerigen Laboratories
Supplier-Nr:	HF-211B7H2