CD2, Recombinant, Human, aa25-209, His-Tag (T-cell Surface Antigen CD2, LFA-2, SRBC, T11)

CD2, also known as T-cell surface antigen CD2, is a cell adhesion molecule found on the surface of T cells and natural killer (NK) cells. It interacts with other adhesion molecules, such as lymphocyte function- associated antigen-3 (LFA-3/CD58) in humans, or CD48 in rodents. CD2 is a specific marker for T cells and NK cells. The great majority of T cell lymphomas and leukaemias also express CD2, making it possible to use the presence of the antigen to distinguish these conditions from B cell neoplasms. Source: Recombinant protein corresponding to aa24-188 from human CD2 protein, fused to His-Tag at C-terminal, expressed in insect cell. Molecular Weight: ~22.3kD (194aa), 28-40kD (SDS-PAGE under reducing conditions.), Endotoxin: <1EU/1ug (determined by LAL method), AA Sequence: ADPKEITNAL ETWGALGQDI NLDIPSFQMS DDIDDIKWEK TSDKKKIAQF RKEKETFKEK DTYKLFKNGT LKIKHLKTDD QDIYKVSIYD TKGKNVLEKI FDLKIQERVS KPKISWTCIN TTLTCEVMNG TDPELNLYQD GKHLKLSQRV ITHKWTTSLS AKFKCTAGNK VSKESSVEPV SCPEKGLDHH HHHH, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.