CD19 Protein (recombinant human)

CD19 Protein (recombinant human)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
G-RPCB1162.10 10 µg - - -

9 - 20 business days*

226.00€
 
Protein function: Functions as coreceptor for the B-cell antigen receptor complex (BCR) on... more
Product information "CD19 Protein (recombinant human)"
Protein function: Functions as coreceptor for the B-cell antigen receptor complex (BCR) on B-lymphocytes. Decreases the threshold for activation of downstream signaling pathways and for triggering B-cell responses to antigens (PubMed:2463100, PubMed:1373518, PubMed:16672701). Activates signaling pathways that lead to the activation of phosphatidylinositol 3-kinase and the mobilization of intracellular Ca(2+) stores (PubMed:9382888, PubMed:9317126, PubMed:12387743, PubMed:16672701). Is not required for early steps during B cell differentiation in the blood marrow (PubMed:9317126). Required for normal differentiation of B-1 cells. Required for normal B cell differentiation and proliferation in response to antigen challenges (PubMed:2463100, PubMed:1373518). Required for normal levels of serum immunoglobulins, and for production of high-affinity antibodies in response to antigen challenge (PubMed:9317126, PubMed:12387743, PubMed:16672701). [The UniProt Consortium]
Keywords: CD19, B-lymphocyte antigen CD19, Differentiation antigen CD19, T-cell surface antigen Leu-12, B-lymphocyte surface antigen B4
Supplier: Assay Genie
Supplier-Nr: RPCB1162

Properties

Conjugate: No
Host: Human cells
Species reactivity: human
Purity: >90% (SDS-PAGE)

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
or to request a certificate of analysis.
Read, write and discuss reviews... more
Customer review for "CD19 Protein (recombinant human)"
Write a review
or to review a product.
Viewed