CASTOR2 (human), recombinant protein

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-PP-6716.20	20 µg	-	-	-	Request delivery time estimate		90.00€
ABS-PP-6716.100	100 µg	-	-	-	Request delivery time estimate		180.00€

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Protein function: Functions as a negative regulator of the TORC1 signaling pathway through the... more

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Product information "CASTOR2 (human), recombinant protein"

Protein function: Functions as a negative regulator of the TORC1 signaling pathway through the GATOR complex. As part of homodimers or heterodimers with CASTOR1, directly binds and inhibits the GATOR subcomplex GATOR2 and thereby mTORC1. Does not directly bind arginine, but binding of arginine to CASTOR1 disrupts the interaction of CASTOR2- containing heterodimers with GATOR2 which can in turn activate mTORC1 and the TORC1 signaling pathway. [The UniProt Consortium]

Keywords:	Cytosolic arginine sensor for mTORC1 subunit 2, Cellular arginine sensor for mTORC1 protein 2, GATS-like protein 2, Recombinant Human CASTOR2 Protein
Supplier:	Absea
Supplier-Nr:	PP-6716

Properties

Conjugate:	No
Host:	E.coli
Species reactivity:	human
MW:	37 kD
Format:	Solution

Database Information

KEGG ID :	K23081 \| Matching products
UniProt ID :	A6NHX0 \| Matching products
Gene ID :	GeneID 729438 \| Matching products

Handling & Safety

Storage:	-20°C (avoid repeat freezing and thawing cycles)
Shipping:	-20°C (International: -20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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