CASTOR1 (human), recombinant protein

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-PP-6715-L.20	20 µg	-	-	-	10 - 15 business days*		115.00€
ABS-PP-6715-L.100	100 µg	-	-	-	10 - 15 business days*		205.00€

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Protein function: Functions as an intracellular arginine sensor within the amino acid-sensing... more

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Product information "CASTOR1 (human), recombinant protein"

Protein function: Functions as an intracellular arginine sensor within the amino acid-sensing branch of the TORC1 signaling pathway. As a homodimer or a heterodimer with CASTOR2, binds and inhibits the GATOR subcomplex GATOR2 and thereby mTORC1. Binding of arginine to CASTOR1 allosterically disrupts the interaction of CASTOR1-containing dimers with GATOR2 which can in turn activate mTORC1 and the TORC1 signaling pathway. [The UniProt Consortium]

Keywords:	Cytosolic arginine sensor for mTORC1 subunit 1, Cellular arginine sensor for mTORC1 protein 1, GATS-like protein 3, Recombinant Human CASTOR1 Protein
Supplier:	Absea
Supplier-Nr:	PP-6715-L

Properties

Conjugate:	No
Host:	E.coli
Species reactivity:	human
MW:	15 kD
Format:	Lyophilized

Database Information

KEGG ID :	K23080 \| Matching products
UniProt ID :	Q8WTX7 \| Matching products
Gene ID :	GeneID 652968 \| Matching products

Handling & Safety

Storage:	-20°C (protect from light & moisture)
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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