cAMP-dependent Protein Kinase Inhibitor ß/PKI-ß Protein(N-6His) (recombinant human)

Protein Construction: Recombinant Human cAMP-dependent Protein Kinase Inhibitor beta is produced by our E.coli expression system and the target gene encoding Met1-Lys78 is expressed with a 6His tag at the N-terminus. Sequence: Met 1-Lys78. Fusion tag: N-6His Endotoxin: < 1.0 EU per µg as determined by the LAL method. Apparent Molecular Mass: 16 kDa. Protein function: cAMP-Dependent Protein Kinase Inhibitor ß (PKI-ß) is a member of the PKI family. As a member of the cAMP-dependent protein kinase inhibitor family,It has been shown that PKI-ß is an extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains. It may play a role in the protein kinase A (PKA) pathway by interacting with the catalytic subunit of PKA, and overexpression of this gene may play a role in prostate cancer. Protein function: Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains. [The UniProt Consortium]