Calsequestrin 1 (human), recombinant protein

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-PP-4413-L.20	20 µg	-	-	-	Request delivery time estimate		115.00€
ABS-PP-4413-L.100	100 µg	-	-	-	Request delivery time estimate		205.00€

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Protein function: Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein... more

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Product information "Calsequestrin 1 (human), recombinant protein"

Protein function: Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle (PubMed:28895244). Calcium ions are bound by clusters of acidic residues at the protein surface, often at the interface between subunits. Can bind around 80 Ca(2+) ions (PubMed:28895244). Regulates the release of lumenal Ca(2+) via the calcium release channel RYR1, this plays an important role in triggering muscle contraction. Negatively regulates store-operated Ca(2+) entry (SOCE) activity (PubMed:27185316). [The UniProt Consortium]

Keywords:	Calsequestrin-1, Calmitine, Calsequestrin, skeletal muscle isoform, Recombinant Human CASQ1 Protein
Supplier:	Absea
Supplier-Nr:	PP-4413-L

Properties

Conjugate:	No
Host:	E.coli
Species reactivity:	human
MW:	43 kD
Format:	Lyophilized

Database Information

KEGG ID :	K23468 \| Matching products
UniProt ID :	P31415 \| Matching products
Gene ID :	GeneID 844 \| Matching products

Handling & Safety

Storage:	-20°C (protect from light & moisture)
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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