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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| G-RPCB0097.100 | 100 µg | - | - |
9 - 20 business days* |
1,645.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Endotoxin level: < 1 EU/µg of the protein by LAL method. Protein function: Key regulator of... more
Product information "Biotinylated Recombinant Mouse GARP&Latent TGF beta 1 Complex Protein"
Endotoxin level: < 1 EU/µg of the protein by LAL method. Protein function: Key regulator of transforming growth factor beta (TGFB1, TGFB2 and TGFB3) that controls TGF-beta activation by maintaining it in a latent state during storage in extracellular space (PubMed:25127859). Associates specifically via disulfide bonds with the Latency-associated peptide (LAP), which is the regulatory chain of TGF-beta, and regulates integrin-dependent activation of TGF-beta (PubMed:25127859, PubMed:28912269). Able to outcompete LTBP1 for binding to LAP regulatory chain of TGF-beta. Controls activation of TGF-beta-1 (TGFB1) on the surface of activated regulatory T-cells (Tregs) (PubMed:25127859). Required for epithelial fusion during palate development by regulating activation of TGF-beta-3 (TGFB3) (PubMed:28912269). [The UniProt Consortium]
| Keywords: | GARP, Garpin, Glycoprotein A repetitions predominant, Leucine-rich repeat-containing protein 32, Transforming growth factor beta activator LRRC32 |
| Supplier: | Assay Genie |
| Supplier-Nr: | RPCB0097 |
Properties
| Conjugate: | Biotin |
| Species reactivity: | mouse |
| Purity: | >95% (TrisBis PAGE, >95% SECHPLC) |
Database Information
| UniProt ID : | G3XA59 | Matching products |
| Gene ID : | GeneID 434215 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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