Biotinylated Recombinant Human TNFRSF10A/DR4/TRAIL-R1/CD261 Protein

Biotinylated Recombinant Human TNFRSF10A/DR4/TRAIL-R1/CD261 Protein
Item number Size Datasheet Manual SDS Delivery time Quantity Price
G-RPCB0022.100 100 µg - - -

9 - 20 business days*

1,258.00€
 
Endotoxin level: < 1 EU/µg of the protein by LAL method. Protein function: Receptor for the... more
Product information "Biotinylated Recombinant Human TNFRSF10A/DR4/TRAIL-R1/CD261 Protein"
Endotoxin level: < 1 EU/µg of the protein by LAL method. Protein function: Receptor for the cytotoxic ligand TNFSF10/TRAIL (PubMed:26457518). The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis (PubMed:19090789). Promotes the activation of NF- kappa-B (PubMed:9430227). [The UniProt Consortium]
Keywords: APO2, CD261, TRAIL-R1, TNFRSF10A, Death receptor 4, TRAIL receptor 1, TNF-related apoptosis-inducing ligand receptor 1, Tumor necrosis factor receptor superfamily member 10A
Supplier: Assay Genie
Supplier-Nr: RPCB0022

Properties

Conjugate: Biotin
Species reactivity: human
Purity: >95% (TrisBis PAGE and HPLC)

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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