Biotinylated Recombinant Human KLRB1/CD161 Protein

Biotinylated Recombinant Human KLRB1/CD161 Protein
Item number Size Datasheet Manual SDS Delivery time Quantity Price
G-RPCB0509.100 100 µg - - -

9 - 20 business days*

1,032.00€
 
Endotoxin level: < 1 EU/µg of the protein by LAL method. Protein function: Plays an inhibitory... more
Product information "Biotinylated Recombinant Human KLRB1/CD161 Protein"
Endotoxin level: < 1 EU/µg of the protein by LAL method. Protein function: Plays an inhibitory role on natural killer (NK) cells cytotoxicity. Activation results in specific acid sphingomyelinase/SMPD1 stimulation with subsequent marked elevation of intracellular ceramide. Activation also leads to AKT1/PKB and RPS6KA1/RSK1 kinases stimulation as well as markedly enhanced T-cell proliferation induced by anti-CD3. Acts as a lectin that binds to the terminal carbohydrate Gal-alpha(1,3)Gal epitope as well as to the N- acetyllactosamine epitope. Binds also to CLEC2D/LLT1 as a ligand and inhibits NK cell-mediated cytotoxicity as well as interferon-gamma secretion in target cells. [The UniProt Consortium]
Keywords: CD161, KLRB1, CLEC5B, NKR-P1A, HNKR-P1a, C-type lectin domain family 5 member B, Natural killer cell surface protein P1A, Killer cell lectin-like receptor subfamily B member 1
Supplier: Assay Genie
Supplier-Nr: RPCB0509

Properties

Conjugate: Biotin
Species reactivity: human
Purity: >95% (SDS-PAGE, >95% HPLC)

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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