Biotinylated Human Her2/ErbB2 Domain 4 Protein

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
KT-HER-HM404B-100UG	100 µg		-		7 - 12 business days*		589.00€
KT-HER-HM404B-500UG	500 µg		-		7 - 12 business days*		1,964.00€

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Recombinant Biotinylated Human Her2/ErbB2 Domain 4 Protein is expressed from HEK293 with His tag... more

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Product information "Biotinylated Human Her2/ErbB2 Domain 4 Protein"

Recombinant Biotinylated Human Her2/ErbB2 Domain 4 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Pro489-Cys630. ErbB2, also called Neu and Her2 (human epidermal growth factor receptor 2), is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors. ErbB family members serve as receptors for the epidermal growth factor (EGF) family of growth factors.Upon ERBB2 activation, the MEMO1-RHOA-DIAPH1 signaling pathway elicits the phosphorylation and thus the inhibition of GSK3B at cell membrane. This prevents the phosphorylation of APC and CLASP2, allowing its association with the cell membrane.

Supplier:	KACTUS
Supplier-Nr:	HER-HM404B

Properties

Conjugate:	Biotin
Host:	Human cells
Species reactivity:	human
MW:	18.5 kD
Purity:	>95% (Tris-Bis PAGE),>95% (HPLC)
Format:	Lyophilized

Database Information

UniProt ID :	P04626 \| Matching products
Gene ID :	GeneID 2064 \| Matching products

Handling & Safety

Storage:	-80°C (avoid repeat freezing and thawing cycles)
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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