Biotinylated Human APOE3/Apolipoprotein E Protein (Primary Amine Labeling)

Recombinant Biotinylated Human APOE3/Apolipoprotein E Protein (Primary Amine Labeling) is expressed from HEK293 with His tag at the N-Terminus.It contains Lys19-His317. Apolipoprotein E (apoE) is a lipid carrier in both the peripheral and the central nervous systems. Lipid-loaded apoE lipoprotein particles bind to several cell surface receptors to support membrane homeostasis and injury repair in the brain. Considering prevalence and relative risk magnitude, the epsilon4 allele of the APOE gene is the strongest genetic risk factor for late-onset Alzheimer's disease (AD).