BDCA-2[Biotin], His & Avi, Human

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
GSC-Z04415-100	100 µg		-		Request delivery time estimate		887.00€
GSC-Z04415-500	500 µg		-		Request delivery time estimate		2,943.00€

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BDCA-2 is a novel type II C-type lectin specifically expressed by plasmacytoid dendritic cells... more

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Product information "BDCA-2[Biotin], His & Avi, Human"

BDCA-2 is a novel type II C-type lectin specifically expressed by plasmacytoid dendritic cells (PDCs) that can internalize antigen for presentation to T cells. Furthermore, signaling via BDCA-2 may play a role in switching from interferon (IFN)-alpha/beta-controlled to interleukin (IL)-12-controlled immune response pathways, as triggering of BDCA-2 potently inhibits secretion of IFN-alpha/beta by PDCs and thereby promotes IL-12 p70 production in PDCs and other cells.

Keywords:	CLEC4C, Dendritic lectin, Blood dendritic cell antigen 2, C-type lectin superfamily member 7, C-type lectin domain family 4 member C
Supplier:	GenScript
Supplier-Nr:	Z04415

Properties

Conjugate:	Biotin
Species reactivity:	human
MW:	22.7 kD
Purity:	>90% (Bis-Tris PAGE)

Database Information

KEGG ID :	K06723 \| Matching products
UniProt ID :	Q8WTT0 \| Matching products
Gene ID :	GeneID 170482 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	-20°C (International: °C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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