ATXN7L3 PrEST Antigen

ATXN7L3 PrEST Antigen
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ATA-APrEST92451.100 100 µl - -

7 - 10 business days*

264.00€
 
Protein function: Component of the transcription regulatory histone acetylation (HAT) complex... more
Product information "ATXN7L3 PrEST Antigen"
Protein function: Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B (PubMed:18206972, PubMed:21746879). The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and ENY2 into the SAGA complex (PubMed:18206972). Regulates H2B monoubiquitination (H2Bub1) levels. Affects subcellular distribution of ENY2, USP22 and ATXN7L3B (PubMed:27601583). [The UniProt Consortium] Buffer: PBS and 1M Urea, pH 7.4.
Keywords: Ataxin-7-like protein 3, SAGA-associated factor 11 homolog
Supplier: Atlas Antibodies
Supplier-Nr: APrEST92451

Properties

Application: Control antigen
Conjugate: No
Host: E.coli
Species reactivity: human

Database Information

UniProt ID : Q14CW9 | Matching products
Gene ID : GeneID 56970 | Matching products

Handling & Safety

Storage: -20°C (avoid repeat freezing and thawing cycles)
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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