ARHGEF4 (human), recombinant protein

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-PP-9242-L.20	20 µg		-	-	Request delivery time estimate		115.00€
ABS-PP-9242-L.100	100 µg		-	-	Request delivery time estimate		205.00€

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Protein function: Acts as guanine nucleotide exchange factor (GEF) for RHOA, RAC1 and CDC42... more

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Product information "ARHGEF4 (human), recombinant protein"

Protein function: Acts as guanine nucleotide exchange factor (GEF) for RHOA, RAC1 and CDC42 GTPases. Binding of APC may activate RAC1 GEF activity. The APC-ARHGEF4 complex seems to be involved in cell migration as well as in E-cadherin-mediated cell-cell adhesion. Required for MMP9 up- regulation via the JNK signaling pathway in colorectal tumor cells. Involved in tumor angiogenesis and may play a role in intestinal adenoma formation and tumor progression. [The UniProt Consortium]

Keywords:	Rho guanine nucleotide exchange factor 4, APC-stimulated guanine nucleotide exchange factor 1, Asef, Asef1, Recombinant Human ARHGEF4 Protein
Supplier:	Absea
Supplier-Nr:	PP-9242-L

Properties

Conjugate:	No
Host:	E.coli
Species reactivity:	human
MW:	15 kD
Format:	Lyophilized

Database Information

KEGG ID :	K05769 \| Matching products
UniProt ID :	Q9NR80 \| Matching products
Gene ID :	GeneID 50649 \| Matching products

Handling & Safety

Storage:	-20°C (protect from light & moisture)
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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