ARHGAP18 (human), recombinant protein

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-PP-5214-L.20	20 µg		-	-	Request delivery time estimate		115.00€
ABS-PP-5214-L.100	100 µg		-	-	Request delivery time estimate		205.00€

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Protein function: Rho GTPase activating protein that suppresses F-actin polymerization by... more

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Product information "ARHGAP18 (human), recombinant protein"

Protein function: Rho GTPase activating protein that suppresses F-actin polymerization by inhibiting Rho. Rho GTPase activating proteins act by converting Rho-type GTPases to an inactive GDP-bound state (PubMed:21865595). Plays a key role in tissue tension and 3D tissue shape by regulating cortical actomyosin network formation. Acts downstream of YAP1 and inhibits actin polymerization, which in turn reduces nuclear localization of YAP1 (PubMed:25778702). Regulates cell shape, spreading, and migration (PubMed:21865595). [The UniProt Consortium]

Keywords:	Rho GTPase-activating protein 18, MacGAP, Rho-type GTPase-activating protein 18, Recombinant Human ARHGAP18 Protein
Supplier:	Absea
Supplier-Nr:	PP-5214-L

Properties

Conjugate:	No
Host:	E.coli
Species reactivity:	human
MW:	37 kD
Format:	Lyophilized

Database Information

KEGG ID :	K20639 \| Matching products
UniProt ID :	Q8N392 \| Matching products
Gene ID :	GeneID 93663 \| Matching products

Handling & Safety

Storage:	-20°C (protect from light & moisture)
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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