ANXA2, His, Human

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
GSC-Z05028-100	100 µg		-		Request delivery time estimate		457.00€
GSC-Z05028-500	500 µg		-		Request delivery time estimate		1,505.00€

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ANXA2, highly expressed in invasive breast cancer cells, is closely related with poor prognosis,... more

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Product information "ANXA2, His, Human"

ANXA2, highly expressed in invasive breast cancer cells, is closely related with poor prognosis, and acts as a molecular switch to EGFR activation. ANXA2 expression is inversely correlated with cell sensitivity to gefitinib. Knockdown of ANXA2 expression in MDA-MB-231 cells increased the gefitinib induced cell death. When ANXA2 was overexpressed in MCF7 cells, the gefitinib induced cell death was decreased. Furthermore, the phosphorylation of ANXA2 at Tyr23 is negatively correlated with the sensitivity of TNBC to gefitinib.

Keywords:	p36, ANXA2, Annexin-2, Protein I, Annexin A2, Annexin II, Lipocortin II, Chromobindin-8, Calpactin I heavy chain, Calpactin-1 heavy chain, Placental anticoagulant protein IV
Supplier:	GenScript
Supplier-Nr:	Z05028

Properties

Conjugate:	No
Species reactivity:	human
MW:	39.6 kD
Purity:	>95% (Bis-Tris PAGE)

Database Information

KEGG ID :	K17092 \| Matching products
UniProt ID :	P07355 \| Matching products
Gene ID :	GeneID 302 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+4°C (International: °C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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