AMIGO2, His, Human

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
GSC-Z05017-100	100 µg		-		Request delivery time estimate		457.00€
GSC-Z05017-500	500 µg		-		Request delivery time estimate		1,505.00€

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Bromodomain and extraterminal domain inhibitors (BETi) represent promising therapeutic agents for... more

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Product information "AMIGO2, His, Human"

Bromodomain and extraterminal domain inhibitors (BETi) represent promising therapeutic agents for metastatic melanoma, yet their mechanism of action remains unclear. Here we interrogated the transcriptional effects of BETi and identified AMIGO2, a transmembrane molecule, as a BET target gene essential for melanoma cell survival. AMIGO2 is upregulated in melanoma cells and tissues compared to human melanocytes and nevi, and AMIGO2 silencing in melanoma cells induces G1/S arrest followed by apoptosis.

Keywords:	AMIGO2, AMIGO-2, Alivin-1, Amphoterin-induced protein 2, Differentially expressed in gastric adenocarcinomas
Supplier:	GenScript
Supplier-Nr:	Z05017

Properties

Conjugate:	No
Species reactivity:	human
MW:	42 kD
Purity:	>95% (Bis-Tris PAGE)

Database Information

KEGG ID :	K22529 \| Matching products
UniProt ID :	Q86SJ2 \| Matching products
Gene ID :	GeneID 347902 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+4°C (International: °C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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