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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| ABS-PP-9590-L.20 | 20 µg | - | - |
10 - 15 business days* |
115.00€
|
||
| ABS-PP-9590-L.100 | 100 µg | - | - |
10 - 15 business days* |
205.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Catalyzes the methylation of 5-carboxymethyl uridine to 5- methylcarboxymethyl... more
Product information "ALKBH8 (human), recombinant protein"
Protein function: Catalyzes the methylation of 5-carboxymethyl uridine to 5- methylcarboxymethyl uridine at the wobble position of the anticodon loop in tRNA via its methyltransferase domain (PubMed:20123966, PubMed:20308323, PubMed:31079898). Catalyzes the last step in the formation of 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in target tRNA (PubMed:20123966, PubMed:20308323). Has a preference for tRNA(Arg) and tRNA(Glu), and does not bind tRNA(Lys)(PubMed:20308323). Binds tRNA and catalyzes the iron and alpha-ketoglutarate dependent hydroxylation of 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in tRNA via its dioxygenase domain, giving rise to 5-(S)- methoxycarbonylhydroxymethyluridine, has a preference for tRNA(Gly) (PubMed:21285950). Required for normal survival after DNA damage (PubMed:20308323). May inhibit apoptosis and promote cell survival and angiogenesis (PubMed:19293182). [The UniProt Consortium]
| Keywords: | Alkylated DNA repair protein alkB homolog 8, Probable alpha-ketoglutarate-dependent dioxygenase ABH8, S-adenosyl-L-methionine-dependent tRNA methyltransferase ABH8, tRNA, carboxymethyluridine(34)-5-O)-methyltransferase ABH8, Recombinant Human ALKBH8 Prote |
| Supplier: | Absea |
| Supplier-Nr: | PP-9590-L |
Properties
| Conjugate: | No |
| Host: | E.coli |
| Species reactivity: | human |
| MW: | 16.5 kD |
| Format: | Lyophilized |
Database Information
| KEGG ID : | K10770 | Matching products |
| UniProt ID : | Q96BT7 | Matching products |
| Gene ID : | GeneID 91801 | Matching products |
Handling & Safety
| Storage: | -20°C (protect from light & moisture) |
| Shipping: | +20°C (International: +20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
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