AFG3L2 (human), recombinant protein

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-PP-2969-L.20	20 µg		-	-	Request delivery time estimate		115.00€
ABS-PP-2969-L.100	100 µg		-	-	Request delivery time estimate		205.00€

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Protein function: ATP-dependent protease which is essential for axonal and neuron development. In... more

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Product information "AFG3L2 (human), recombinant protein"

Protein function: ATP-dependent protease which is essential for axonal and neuron development. In neurons, mediates degradation of SMDT1/EMRE before its assembly with the uniporter complex, limiting the availability of SMDT1/EMRE for MCU assembly and promoting efficient assembly of gatekeeper subunits with MCU (PubMed:27642048). Required for the maturation of paraplegin (SPG7) after its cleavage by mitochondrial-processing peptidase (MPP), converting it into a proteolytically active mature form. Required for the maturation of PINK1 into its 52kDa mature form after its cleavage by mitochondrial-processing peptidase (MPP) (PubMed:22354088). [The UniProt Consortium]

Keywords:	AFG3-like protein 2, Paraplegin-like protein, Recombinant Human AFG3L2 Protein
Supplier:	Absea
Supplier-Nr:	PP-2969-L

Properties

Conjugate:	No
Host:	E.coli
Species reactivity:	human
MW:	28 kD
Format:	Lyophilized

Database Information

KEGG ID :	K08956 \| Matching products
UniProt ID :	Q9Y4W6 \| Matching products
Gene ID :	GeneID 10939 \| Matching products

Handling & Safety

Storage:	-20°C (protect from light & moisture)
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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