AcMNPV Major Envelope Glycoprotein (recombinant)

Autographa californica multiple nucleopolyhedrovirus (AcMNPV) major envelope glycoprotein is a class III viral fusion protein. AcMNPV is a double-stranded DNA insect virus and member of the Baculoviridae family. AcMNPV major envelope glycoprotein exists as a trimer and is composed of five domains in the low pH, post-fusion state that is highly post-translationally modified via glycosylation sites and a palmitoylation site at the C-terminus. It is expressed on the surface of infected cells and budded virions. AcMNPV major envelope glycoprotein is involved in viral envelope-host cell endosome membrane fusion in a low pH-dependent manner and in virion budding. Lipoplexes containing AcMNPV major envelope glycoprotein have been used for gene delivery to mammalian cells, which can be inhibited by an AcMNPV major envelope glycoprotein neutralizing antibody. Cayman's AcMNPV Major Envelope Glycoprotein protein consists of 472 amino acids, has a calculated molecular weight of 54.2 kDa, and a predicted N-terminus of Ala21 after signal peptide cleavage.Synonyms: AcMNPV GP64, Autographa californica Multicapsid Nucleopolyhedrovirus Major Envelope Glycoprotein, Autographa californica Multiple Nucleopolyhedrovirus Major Envelope Glycoprotein. Purity: >95% estimated by SDS-PAGE. Endotoxin Testing: <1.0 EU/µg determined by the LAL endotoxin assay. Source: Recombinant AcMNPV (strain E2) C-terminal His-tagged major envelope glycoprotein expressed in insect cells. Amino Acids: 21-481. MW: 54.2 kDa. Formulation: (Request formulation change), Lyophilized from sterile 20 mM Tris, pH 7.5, 500 mM sodium chloride, and 10% glycerol. UniProt Accession #: P17501.