ABCC10 (human), recombinant protein

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-PP-16239-L.20	20 µg		-	-	10 - 15 business days*		115.00€
ABS-PP-16239-L.100	100 µg		-	-	10 - 15 business days*		205.00€

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Protein function: ATP-dependent transporter of the ATP-binding cassette (ABC) family that... more

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Product information "ABCC10 (human), recombinant protein"

Protein function: ATP-dependent transporter of the ATP-binding cassette (ABC) family that actively extrudes physiological compounds, and xenobiotics from cells. Lipophilic anion transporter that mediates ATP-dependent transport of glucuronide conjugates such as estradiol-17-beta-o- glucuronide and GSH conjugates such as leukotriene C4 (LTC4) (PubMed:12527806, PubMed:15256465). Mediates multidrug resistance (MDR) in cancer cells by preventing the intracellular accumulation of certain antitumor drugs, such as, docetaxel and paclitaxel (PubMed:15256465, PubMed:23087055). Does not transport glycocholic acid, taurocholic acid, MTX, folic acid, cAMP, or cGMP (PubMed:12527806). [The UniProt Consortium]

Keywords:	MRP7, ABCC10, Multidrug resistance-associated protein 7, ATP-binding cassette sub-family C member 10
Supplier:	Absea
Supplier-Nr:	PP-16239-L

Properties

Conjugate:	No
Host:	E.coli
Species reactivity:	human
MW:	35 kD
Purity:	>85%
Format:	Lyophilized

Database Information

KEGG ID :	K05674 \| Matching products
UniProt ID :	Q5T3U5 \| Matching products
Gene ID :	GeneID 89845 \| Matching products

Handling & Safety

Storage:	-20°C (protect from light & moisture)
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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