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Item number: DIM-FLP120752.10
The protein encoded by this gene is a hyperpolarization-activated cation channel involved in the generation of native pacemaker activity in the heart and in the brain. The encoded protein is activated by cAMP and can produce a fast, large current. Defects in this gene were noted as a possible cause of some forms of...
| Keywords: | HCN2, BCNG2, BCNG-2, Brain cyclic nucleotide-gated channel 2, Potassium/sodium hyperpolarization-activated cyclic... |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 97 kD |
From 1,185.00€
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Item number: DIM-FLP120754.10
This gene encodes a member of the hyperpolarization-activated cyclic nucleotide-gated potassium channels. The encoded protein shows slow kinetics of activation and inactivation, and is necessary for the cardiac pacemaking process. This channel may also mediate responses to sour stimuli. Mutations in this gene have...
| Keywords: | HCN4, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 129 kD |
From 1,185.00€
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Item number: DIM-FLP120756.10
The protein encoded by this gene is a membrane protein that can form a non-selective channel permeable to calcium and other cations. The encoded protein appears to be induced to form channels by a receptor tyrosine kinase-activated phosphatidylinositol second messenger system and also by depletion of intracellular...
| Keywords: | TRP3, TrpC3, TRP-3, hTrp3, TRPC3, hTrp-3, Transient receptor protein 3, Short transient receptor potential channel 3 |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 96 kD |
From 1,185.00€
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Item number: DIM-FLP120765.10
This gene encodes a member of the transient receptor potential (TRP) protein family, which is a diverse group of proteins with structural features typical of ion channels. This protein plays an important role in taste transduction, and has characteristics of a calcium-activated, non-selective cation channel that...
| Keywords: | LTrpC5, LTrpC-5, MLSN1- and TRP-related gene 1 protein, Long transient receptor potential channel 5, Transient receptor... |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 131.5 kD |
From 1,185.00€
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Item number: DIM-FLP120773.10
This gene encodes a member of the polycystin protein family. The encoded protein contains multiple transmembrane domains, and cytoplasmic N- and C-termini. The protein may be an integral membrane protein involved in cell-cell/matrix interactions. This protein functions as a calcium-regulated nonselective cation...
| Keywords: | PKD2L1, Polycystin-L, Polycystin-L1, Polycystin-2L1, Polycystin-2 homolog, Polycystic kidney disease 2-like 1 protein |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 92 kD |
From 1,185.00€
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Item number: DIM-FLP120777.10
This gene encodes a member of the OSM9-like transient receptor potential channel (OTRPC) subfamily in the transient receptor potential (TRP) superfamily of ion channels. The encoded protein is a Ca2 -permeable, nonselective cation channel that is thought to be involved in the regulation of systemic osmotic pressure....
| Keywords: | VRL2, TRPV4, VRL-2, TrpV4, TRP12, VR-OAC, OTRPC4, Osm-9-like TRP channel 4, Vanilloid receptor-like protein 2, Vanilloid... |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 98.3 kD |
From 1,185.00€
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Item number: DIM-FLP120778.10
This gene is a member of the transient receptor family and the TrpV subfamily. The calcium-selective channel encoded by this gene has 6 transmembrane-spanning domains, multiple potential phosphorylation sites, an N-linked glycosylation site, and 5 ANK repeats. This protein forms homotetramers or heterotetramers and...
| Keywords: | ECaC, CaT2, TrpV5, TRPV5, ECaC1, OTRPC3, Osm-9-like TRP channel 3, Calcium transport protein 2, Epithelial calcium channel... |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 82.6 kD |
From 1,185.00€
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Item number: DIM-FLP120780.10
The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit B of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in...
| Keywords: | HTR3B, 5-HT3B, 5-HT3-B, Serotonin receptor 3B, 5-hydroxytryptamine receptor 3B |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 50.3 kD |
From 1,185.00€
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Item number: DIM-FLP120781.10
The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit C of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in...
| Keywords: | HTR3C, 5-HT3C, 5-HT3-C, Serotonin receptor 3C, 5-hydroxytryptamine receptor 3C |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 50.2 kD |
From 1,185.00€
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Item number: DIM-FLP120794.10
Neuronal acetylcholine receptors are homo- or heteropentameric complexes composed of homologous alpha and beta subunits. They belong to a superfamily of ligand-gated ion channels which allow the flow of sodium and potassium across the plasma membrane in response to ligands such as acetylcholine and nicotine. This...
| Keywords: | CHRNB2, Neuronal acetylcholine receptor subunit beta-2 |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 57 kD |
From 1,185.00€
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Item number: DIM-FLP120799.10
The mammalian muscle-type acetylcholine receptor is a transmembrane pentameric glycoprotein with two alpha subunits, one beta, one delta, and one epsilon (in adult skeletal muscle) or gamma (in fetal and denervated muscle) subunit. This gene, which encodes the gamma subunit, is expressed prior to the thirty-third...
| Keywords: | CHRNG, ACHRG, Acetylcholine receptor subunit gamma |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 57.9 kD |
From 1,185.00€
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Item number: DIM-FLP120803.10
Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct...
| Keywords: | GABRA4, GABA(A) receptor subunit alpha-4, Gamma-aminobutyric acid receptor subunit alpha-4 |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 61.6 kD |
From 1,185.00€
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