15-PGDH (human), recombinant protein

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-PP-10643-L.20	20 µg		-	-	10 - 15 business days*		115.00€
ABS-PP-10643-L.100	100 µg		-	-	10 - 15 business days*		205.00€

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Protein function: Primary enzyme catalyzing the conversion of hydroxylated arachidonic acid... more

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Product information "15-PGDH (human), recombinant protein"

Protein function: Primary enzyme catalyzing the conversion of hydroxylated arachidonic acid species to their corresponding oxidized metabolites (Probable). Prostaglandin inactivation, catalyzes the first step in the catabolic pathway of the prostaglandins. Contributes to the regulation of events that are under the control of prostaglandin levels (PubMed:15574495, PubMed:16828555, PubMed:8086429). Catalyzes the NAD- dependent dehydrogenation of lipoxin A4 to form 15-oxo-lipoxin A4 (PubMed:10837478). Converts 11(R)-HETE to 11-oxo-5,8,12,14-(Z,Z,E,Z)- eicosatetraenoic acid (ETE) (PubMed:21916491). Has hydroxylated docosahexaenoic acid metabolites as substrates (PubMed:25586183). Converts resolvins E1, D1 and D2 to their oxo products which represents a mode of resolvins inactivation and stabilizes their anti-inflammatory actions (PubMed:16757471, PubMed:22844113). [The UniProt Consortium]

Keywords:	15-hydroxyprostaglandin dehydrogenase [NAD(+], 15-PGDH, Eicosanoid/docosanoid dehydrogenase [NAD(+], Prostaglandin dehydrogenase 1, Short chain dehydrogenase/reductase family 36C member 1, Recombinant Human HPGD Protein
Supplier:	Absea
Supplier-Nr:	PP-10643-L

Properties

Conjugate:	No
Host:	E.coli
Species reactivity:	human
MW:	30 kD
Format:	Lyophilized

Database Information

KEGG ID :	K00069 \| Matching products
UniProt ID :	P15428 \| Matching products
Gene ID :	GeneID 3248 \| Matching products

Handling & Safety

Storage:	-20°C (protect from light & moisture)
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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