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NEW
| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| SNB-HP102245 | 1 pair | - |
10 - 15 business days* |
92.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein Function: Cyclic-nucleotide phosphodiesterase that acts as a negative regulator of innate... more
Product information "Human SMPDL3A qPCR Primer Pair"
Protein Function: Cyclic-nucleotide phosphodiesterase that acts as a negative regulator of innate immunity by mediating degradation of 2',3'-cGAMP, thereby inhibiting the cGAS-STING signaling (PubMed:37890481). Specifically linearizes 2',3'-cGAMP into 2'5'-bond pGpA and further hydrolyzes pGpA to produce GpA (PubMed:37890481). Also has in vitro nucleotide phosphodiesterase activity with nucleoside triphosphates, such as ATP (PubMed:25288789, PubMed:26783088). Has in vitro activity with p-nitrophenyl-TMP (PubMed:25288789). Has lower activity with nucleoside diphosphates, and no activity with nucleoside monophosphates (PubMed:25288789, PubMed:26783088, PubMed:28104755). Has in vitro activity with CDP-choline, giving rise to CMP and phosphocholine. Has in vitro activity with CDP-ethanolamine (PubMed:26783088). Does not have sphingomyelin phosphodiesterase activity (PubMed:25288789, PubMed:26783088) [The Uniprot Consortium]
| Keywords: | SMPDL3A, Cyclic GMP-AMP phosphodiesterase SMPDL3A, Acid sphingomyelinase-like phosphodiesterase 3a |
| Supplier: | Sino Biological |
| Supplier-Nr: | HP102245 |
Properties
| Application: | qPCR |
| Species reactivity: | human |
Database Information
| KEGG ID : | K01128 | Matching products |
| UniProt ID : | Q92484 | Matching products |
| Gene ID : | GeneID 10924 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +20°C (International: +20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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