Human HEY1 qPCR Primer Pair

Human HEY1 qPCR Primer Pair
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Item number Size Datasheet Manual SDS Delivery time Quantity Price
SNB-HP103346 1 pair -

10 - 15 business days*

92.00€
 
Protein Function: Transcriptional repressor which binds preferentially to the canonical E box... more
Product information "Human HEY1 qPCR Primer Pair"
Protein Function: Transcriptional repressor which binds preferentially to the canonical E box sequence 5'-CACGTG-3' (PubMed:11095750). Downstream effector of Notch signaling required for cardiovascular development. Specifically required for the Notch-induced endocardial epithelial to mesenchymal transition, which is itself criticial for cardiac valve and septum development. May be required in conjunction with HEY2 to specify arterial cell fate or identity. Promotes maintenance of neuronal precursor cells and glial versus neuronal fate specification. Represses transcription by the cardiac transcriptional activators GATA4 and GATA6 and by the neuronal bHLH factors ASCL1/MASH1 and NEUROD4/MATH3 (PubMed:15485867). Involved in the regulation of liver cancer cells self-renewal (PubMed:25985737) [The Uniprot Consortium]
Keywords: HEY1, HES-related repressor protein 1, Hairy-related transcription factor 1, Cardiovascular helix-loop-helix factor 2, Class B basic helix-loop-helix protein 31, Hairy and enhancer of split-related protein 1, Hairy/enhancer-of-split related with YRPW moti
Supplier: Sino Biological
Supplier-Nr: HP103346

Properties

Application: qPCR
Species reactivity: human

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: +20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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