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NEW
| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| SNB-HP101903 | 1 pair | - |
10 - 15 business days* |
92.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein Function: Dual-specificity kinase which possesses both serine/threonine and tyrosine... more
Product information "Human DYRK1B qPCR Primer Pair"
Protein Function: Dual-specificity kinase which possesses both serine/threonine and tyrosine kinase activities. Plays an essential role in ribosomal DNA (rDNA) double-strand break repair and rDNA copy number maintenance (PubMed:33469661). During DNA damage, mediates transcription silencing in part via phosphorylating and enforcing DSB accumulation of the histone methyltransferase EHMT2 (PubMed:32611815). Enhances the transcriptional activity of TCF1/HNF1A and FOXO1. Inhibits epithelial cell migration. Mediates colon carcinoma cell survival in mitogen-poor environments. Inhibits the SHH and WNT1 pathways, thereby enhancing adipogenesis. In addition, promotes expression of the gluconeogenic enzyme glucose-6-phosphatase catalytic subunit 1 (G6PC1) [The Uniprot Consortium]
| Keywords: | DYRK1B, Mirk protein kinase, Minibrain-related kinase, Dual specificity tyrosine-phosphorylation-regulated kinase 1B |
| Supplier: | Sino Biological |
| Supplier-Nr: | HP101903 |
Properties
| Application: | qPCR |
| Species reactivity: | human |
Database Information
| KEGG ID : | K08825 | Matching products |
| UniProt ID : | Q9Y463 | Matching products |
| Gene ID : | GeneID 9149 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +20°C (International: +20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
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