Human DCUN1D1 qPCR Primer Pair

Human DCUN1D1 qPCR Primer Pair
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Item number Size Datasheet Manual SDS Delivery time Quantity Price
SNB-HP103687 1 pair -

10 - 15 business days*

92.00€
 
Protein Function: Part of an E3 ubiquitin ligase complex for neddylation (PubMed:18826954).... more
Product information "Human DCUN1D1 qPCR Primer Pair"
Protein Function: Part of an E3 ubiquitin ligase complex for neddylation (PubMed:18826954). Promotes neddylation of cullin components of E3 cullin-RING ubiquitin ligase complexes (PubMed:19617556, PubMed:23201271, PubMed:23401859, PubMed:26906416). Acts by binding to cullin-RBX1 complexes in the cytoplasm and promoting their nuclear translocation, enhancing recruitment of E2-NEDD8 (UBE2M-NEDD8) thioester to the complex, and optimizing the orientation of proteins in the complex to allow efficient transfer of NEDD8 from the E2 to the cullin substrates. Involved in the release of inhibitory effets of CAND1 on cullin-RING ligase E3 complex assembly and activity (PubMed:25349211, PubMed:28581483). Also acts as an oncogene facilitating malignant transformation and carcinogenic progression (By similarity) [The Uniprot Consortium]
Keywords: DCUN1D1, DCN1-like protein 1, DCUN1 domain-containing protein 1, Squamous cell carcinoma-related oncogene, Defective in cullin neddylation protein 1-like protein 1
Supplier: Sino Biological
Supplier-Nr: HP103687

Properties

Application: qPCR
Species reactivity: human

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: +20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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