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NEW
| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| SNB-HP101172 | 1 pair | - |
10 - 15 business days* |
92.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein Function: Bifunctional enzyme that catalyzes the last two steps of purine biosynthesis... more
Product information "Human ATIC qPCR Primer Pair"
Protein Function: Bifunctional enzyme that catalyzes the last two steps of purine biosynthesis (PubMed:11948179, PubMed:14756554). Acts as a transformylase that incorporates a formyl group to the AMP analog AICAR (5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) to produce the intermediate formyl-AICAR (FAICAR) (PubMed:10985775, PubMed:11948179, PubMed:9378707). Can use both 10-formyldihydrofolate and 10-formyltetrahydrofolate as the formyl donor in this reaction (PubMed:10985775). Also catalyzes the cyclization of FAICAR to inosine monophosphate (IMP) (PubMed:11948179, PubMed:14756554). Is able to convert thio-AICAR to 6-mercaptopurine ribonucleotide, an inhibitor of purine biosynthesis used in the treatment of human leukemias (PubMed:10985775). Promotes insulin receptor/INSR autophosphorylation and is involved in INSR internalization (PubMed:25687571) [The Uniprot Consortium]
| Keywords: | ATIC, Bifunctional purine biosynthesis protein ATIC, AICAR transformylase/inosine monophosphate cyclohydrolase |
| Supplier: | Sino Biological |
| Supplier-Nr: | HP101172 |
Properties
| Application: | qPCR |
| Species reactivity: | human |
Database Information
| KEGG ID : | K00602 | Matching products |
| UniProt ID : | P31939 | Matching products |
| Gene ID : | GeneID 471 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +20°C (International: +20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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