ZMYND11 (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC

Length: 1584 Sequence: atgtctcgag tccacggtat gcaccctaaa gagaccaccc gtcagctgag cttagctgtg aaagatggtc ttattgtcga aactctaaca gtgggctgca aaggttcaaa agctggtatt gaacaagaag gatattggtt gccaggagat gagattgact gggaaacaga aaatcatgac tggtattgtt ttgaatgcca tttgcctgga gaggtgttga tatgtgacct gtgttttcgt gtgtatcatt ccaagtgttt gtctgatgag ttcaggctta gagacagcag tagtccctgg cagtgcccag tttgcaggag cattaagaag aagaatacaa acaaacagga gatgggcaca tacctcagat tcattgtctc ccgcatgaag gagagggcta tagatcttaa taaaaagggg aaggacaata aacacccgat gtacaggagg ctggtgcact cagctgtgga cgttcccacc attcaagaga aagtgaatga agggaaatac cgaagttatg aagagttcaa agctgatgcc caattgcttc tccacaatac cgtgattttc tatggagaca gtgagcaagc tgacattgcg aggatgctat ataaagacac atgtcatgag ctggatgaac tgcagctttg caagaattgc ttttacttgt caaatgctcg tcctgacaac tggttctgtt atccttgtat acctaatcat gagctggttt gggctaaaat gaaaggtttt gggttttggc cagccaaagt catgcagaaa gaagacaatc aagtcgacgt tcgcttcttt ggccaccacc accagagggc ctggattcct tctgaaaaca ttcaagatat cacagtcaac attcatcggc tgcacgtgaa gcgcagtatg ggttggaaaa aggcctgtga tgagctggag ctgcatcagc gtttcctacg agaagggaga ttttggaaat ctaagaatga ggaccgaggt gaggaagagg cagaatccag tatctcctcc accagtaatg agcagctaaa ggtcactcaa gaaccaagag caaagaaagg acgacgtaat caaagtgtgg agcccaaaaa ggaagaacca gagcctgaaa cagaagcagt aagttctagc caggaaatac ccacgatgcc tcagcccatc gaaaaagtct ccgtgtcaac tcagacaaag aagttaagtg cctcttcacc aagaatgctg catcggagca cccagaccac aaacgacggc gtgtgtcaga gcatgtgcca tgacaaatac accaagatct tcaatgactt caaagaccgg atgaagtcgg accacaagcg ggagacagag cgtgttgtcc gagaagctct ggagaagctg cgttctgaaa tggaagaaga aaagagacaa gctgtaaata aagctgtagc caacatgcag ggtgagatgg acagaaaatg taagcaagta aaggaaaagt gtaaggaaga atttgtagaa gaaatcaaga agctggcaac acagcacaag caactgattt ctcagaccaa gaagaagcag tgggtaaata ccagtctttt Protein function: Chromatin reader that specifically recognizes and binds histone H3.3 trimethylated at 'Lys-36' (H3.3K36me3) and regulates RNA polymerase II elongation. Does not bind other histone H3 subtypes (H3.1 or H3.2). Colocalizes with highly expressed genes and functions as a transcription corepressor by modulating RNA polymerase II at the elongation stage. Binds non-specifically to dsDNA (PubMed:24675531). Acts as a tumor-suppressor by repressing a transcriptional program essential for tumor cell growth. [The UniProt Consortium]