YAF2 (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC, A

Length: 615 Sequence: atgggagaca agaagagccc caccaggccg aagcggcagc cgaagccgtc ctcggatgag ggttactggg actgtagcgt ctgcaccttc cggaacagcg ccgaggcctt caagtgcatg atgtgcgatg tgcggaaggg cacctccacc cgatccacat tgtttgaagt tattgtgagt gcctcgagga ccaaggaacc gttgaaattt ccaatttcag gaaggaaacc tcgacctgtc tcccagttgg ttgcacagca ggttactcag cagtttgtgc ctcctacaca gtcaaagaaa gagaaaaaag ataaagtaga aaaagaaaaa agtgaaaagg aaacaactag caaaaagaat agccataaga aaaccaggcc aagattgaaa aatgtggatc ggagtagtgc tcagcatttg gaagttactg ttggagatct gacagtcatt attacagact ttaaggagaa aacaaagtca ccgcctgcat ctagtgctgc ctctgcagat caacacagtc aaagcggctc tagctctgat aacacagaga gaggaatgtc caggtcatct tcacccagag gagaagcctc atcattgaat ggagaatctc Protein function: Binds to MYC and inhibits MYC-mediated transactivation. Also binds to MYCN and enhances MYCN-dependent transcriptional activation. Increases calpain 2-mediated proteolysis of YY1 in vitro. Component of the E2F6.com-1 complex, a repressive complex that methylates 'Lys-9' of histone H3, suggesting that it is involved in chromatin-remodeling. [The UniProt Consortium]