WBSCR22 (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC

Length: 846 Sequence: atggcgtccc gcggccggcg tccggagcat ggcggacccc cagagctgtt ttatgacgag acagaagccc ggaaatacgt tcgcaactca cggatgattg atatccagac caggatggct gggcgagcat tggagcttct ttatctgcca gagaataagc cctgttacct gctggatatt ggctgtggca ctgggctgag tggaagttat ctgtcagatg aagggcacta ttgggtgggc ctggatatca gccctgccat gctggatgag gctgtggacc gagagataga gggagacctg ctgctggggg atatgggcca gggcatccca ttcaagccag gcacatttga tggttgcatc agcatttctg ctgtgcagtg gctctgtaat gctaacaaga agtctgaaaa ccctgccaag cgcctgtact gcttttttgc ttctcttttt tctgttctcg tccggggatc ccgagctgtc ctgcagctgt accctgagaa ctcagagcag ttggagctga tcacaaccca ggccacaaag gcaggcttct ccggtggcat ggtggtagac taccctaaca gtgccaaagc aaagaaattc tacctctgct tgttttctgg gccttcgacc tttataccag aggggctgag tgaaaatcag gatgaagttg aacccaggga gtctgtgttc accaatgaga ggttcccatt aaggatgtcg aggcggggaa tggtgaggaa gagtcgggca tgggtgctgg agaagaagga gcggcacagg cgccagggca gggaagtcag acctgacacc cagtacaccg gccgcaagcg caagccccgc Protein function: S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(7) position of a guanine in 18S rRNA (PubMed:25851604). Requires the methyltransferase adapter protein TRM112 for full rRNA methyltransferase activity (PubMed:25851604). Involved in the pre-rRNA processing steps leading to small-subunit rRNA production independently of its RNA-modifying catalytic activity (PubMed:25851604). Important for biogenesis end export of the 40S ribosomal subunit independent on its methyltransferase activity (PubMed:24086612). Locus-specific steroid receptor coactivator. Potentiates transactivation by glucocorticoid (NR3C1), mineralocorticoid (NR3C2), androgen (AR) and progesterone (PGR) receptors (PubMed:24488492). Required for the maintenance of open chromatin at the TSC22D3/GILZ locus to facilitate NR3C1 loading on the response elements (PubMed:24488492). Required for maintenance of dimethylation on histone H3 'Lys-79' (H3K79me2), although direct histone methyltransferase activity is not observed in vitro (PubMed:24488492). [The UniProt Consortium]