WBSCR22 (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC

Length: 753 Sequence: atgattgata tccagaccag gatggctggg cgagcattgg agcttcttta tctgccagag aataagccct gttacctgct ggatattggc tgtggcactg ggctgagtgg aagttatctg tcagatgaag ggcactattg ggtgggcctg gatatcagcc ctgccatgct ggatgaggct gtggaccgag agatagaggg agacctgctg ctgggggata tgggccaggg catcccattc aagccaggca catttgatgg ttgcatcagc atttctgctg tgcagtggct ctgtaatgct aacaagaagt ctgaaaaccc tgccaagcgc ctgtactgct tttttgcttc tcttttttct gttctcgtcc ggggatcccg agctgtcctg cagctgtacc ctgagaactc agagcagttg gagctgatca caacccaggc cacaaaggca ggcttctccg gtggcatggt ggtagactac cctaacagtg ccaaagcaaa gaaattctac ctctgcttgt tttctgggcc ttcgaccttt ataccagagg ggctgagtga aaatcaggat gaagttgaac ccagggagtc tgtgttcacc aatgagaggt tcccattaag gatgtcgagg cggggaatgg tgaggaagag tcgggcatgg gtgctggaga agaaggagcg gcacaggcgc cagggcaggg aagtcagacc tgacacccag tacaccggcc gcaagcgcaa gccccgcttc Protein function: S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(7) position of a guanine in 18S rRNA (PubMed:25851604). Requires the methyltransferase adapter protein TRM112 for full rRNA methyltransferase activity (PubMed:25851604). Involved in the pre-rRNA processing steps leading to small-subunit rRNA production independently of its RNA-modifying catalytic activity (PubMed:25851604). Important for biogenesis end export of the 40S ribosomal subunit independent on its methyltransferase activity (PubMed:24086612). Locus-specific steroid receptor coactivator. Potentiates transactivation by glucocorticoid (NR3C1), mineralocorticoid (NR3C2), androgen (AR) and progesterone (PGR) receptors (PubMed:24488492). Required for the maintenance of open chromatin at the TSC22D3/GILZ locus to facilitate NR3C1 loading on the response elements (PubMed:24488492). Required for maintenance of dimethylation on histone H3 'Lys-79' (H3K79me2), although direct histone methyltransferase activity is not observed in vitro (PubMed:24488492). [The UniProt Consortium]