UQCRB (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC,

Length: 336 Sequence: atggctggta agcaggccgt ttcagcatca ggcaagtggc tggatggtat tcgaaaatgg tattacaatg ctgcaggatt caataaactg gggttaatgc gagatgatac aatatacgag gatgaagatg taaaagaagc cataagaaga cttcctgaga acctttataa tgacaggatg tttcgcatta agagggcact ggacctgaac ttgaagcatc agatcttgcc taaagagcag tggaccaaat atgaagagga aaatttctac cttgaaccgt atctgaaaga ggttattcgg gaaagaaaag aaagagaaga atgggcaaag Protein function: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c. [The UniProt Consortium]