UPP2 (Vector pENTR223.1, Accession No. BC033529)

Length: 954 Sequence: atggcttcag ttatacctgc ctccaatagg tccatgagat ctgacaggaa tacatatgtt ggaaaaaggt ttgttcacgt taaaaatcct tacttggatt tgatggatga agacattctc tatcacttgg atttgggaac aaaaacacac aacctaccag caatgtttgg agatgtaaag tttgtctgtg tcggtgggag ccccaacaga atgaaagcat ttgcactgtt tatgcacaag gagctcgggt ttgaggaagc tgaagaagac ataaaagaca tctgtgctgg gacagacaga tactgtatgt acaaaaccgg gcctgtgctc gccatcagtc acggcatggg catcccctcc atttctatta tgcttcatga actcatcaaa ttactccacc atgcacggtg ctgcgatgtc accattatta gaatcggtac atcaggggga atagggattg caccagggac tgttgtaata acggatatag ctgtagactc cttctttaag ccccggtttg aacaggtcat tttggacaac attgtcaccc gaagtactga actggacaaa gaactgtctg aagaactgtt caactgtagc aaagaaatcc ccaacttccc aaccctcgtt ggacatacaa tgtgtaccta tgatttttat gaaggccaag gccgactaga tggagcactg tgctcctttt ccagagaaaa aaagttagac tacttgaaga gagcatttaa agctggtgtc aggaatattg aaatggaatc tacagtgttt gcagctatgt gtggactctg tggtctaaaa gctgctgtgg tctgtgtgac acttctcgac agactcgact gtgatcagat caacttgcct catgatgtcc tggtggagta ccagcaacgg cctcagctcc taatctccaa cttcatcaga cggcggcttg gactttgtga Protein function: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate (PubMed:12849978, PubMed:21855639). The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis (Probable). Shows broad substrate specificity and accepts uridine, deoxyuridine, and thymidine as well as the two pyrimidine nucleoside analogs 5-fluorouridine and 5-fluoro- 2(')-deoxyuridine as substrates (PubMed:12849978). [The UniProt Consortium]