U2AF1L4 (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC

Length: 609 Sequence: atggctgaat atttagcttc gatattcggg actgagaagg acaaggttaa ctgctctttt tactttaaga tcggggtctg ccggcacggg gaccggtgct cccggcttca caacaagccg acattcagcc aggaggtgtt cacagaactg caggagaagt atggggagat tgaagagatg aatgtgtgcg acaaccttgg ggaccacgtc gtgggcaacg tctatgtcaa gttccggagg gaggaggatg gagagcgggc cgtggctgaa ctcagtaacc gctggttcaa cgggcaggct gtgcacggga atgtacccga ggtggcttct gcaacttcat gcatctgcgg cccatttccc agaacctcca gaggcagctc tatgggcggg gacccaggcg caggtcaccc ccgaggttcc atactggcca caatccccga gagaggaacc atcggtgttc ccctgatcac tggcatggcc gcttctgagg ccctggcccc cttacccttc acccccaaca gggacagatg ttcctggcag gacctctcct caaagccccc ttcactctcc tgccccatcc ttcccaggct cccgggctcc Protein function: RNA-binding protein that function as a pre-mRNA splicing factor. Plays a critical role in both constitutive and enhancer- dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3'-splice site selection. Acts by enhancing the binding of U2AF2 to weak pyrimidine tracts. Also participates in the regulation of alternative pre-mRNA splicing. Activates exon 5 skipping of PTPRC during T-cell activation, an event reversed by GFI1. Binds to RNA at the AG dinucleotide at the 3'-splice site. Shows a preference for AGC or AGA. [The UniProt Consortium]