TULP3 (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC,

Length: 1329 Sequence: atggaggctt cgcgctgccg gctcagtccc agcggcgaca gtgtcttcca tgaagaaatg atgaagatgc gacaggctaa gctggattat cagaggctac tacttgagaa gaggcaaagg aaaaagcgcc ttgagccatt tatggtgcag cccaatccag aagccaggct acgtcgggca aagccaaggg ccagtgatga gcagactccc ttggtgaact gtcatactcc ccacagcaat gtcatcttac atggtattga tggtccagct gctgtcctga aaccagacga agttcatgct ccatcagtaa gctcctctgt tgtggaagaa gatgctgaaa acaccgtgga tactgcttcc aagccaggac ttcaggagcg tctccaaaag catgatatct ctgaaagtgt gaacttcgat gaggagactg atggaatatc ccagtcagca tgtttagaaa gacccaattc tgcatcaagc cagaattcaa ccgatacagg cacttccggt tctgctactg ccgcccaacc agctgataac ctcctgggag acatagacta cctggaggac tttgtgtata gtcctgcccc tcaaggtgtc acagtaagat gtcggataat ccgggataaa aggggaatgg atcggggtct cttccccacc tactatatgt acttggaaaa agaagaaaat cagaagatat ttcttcttgc agctagaaag cggaaaaaga gcaaaacagc caactacctt atctccattg atccagttga tttatctcgt gaaggagaaa gttatgtcgg caagcttaga tccaacctca tggggaccaa gtttacagtt tatgaccgtg gcatctgccc catgaagggc cggggtttgg taggagcggc ccacacccgg caggagctgg ctgccatctc ctatgaaaca aacgtacttg gatttaaagg tcctaggaaa atgtctgtga tcattcctgg aatgacactg aatcataagc agatccccta tcagccacaa aacaaccatg acagtttgct ctcaaggtgg cagaacagaa ctatggaaaa tctggttgag ctgcacaaca aggcccccgt ctggaacagt gacactcagt cctatgtcct caacttccgt ggccgggtca ctcaggcgtc tgtgaagaac ttccagatag tccacaaaaa tgaccctgat tatatagtca tgcagtttgg acgtgtggca gatgacgtgt tcacactgga ttacaactac ccactttgtg cagtacaggc ctttggcatc ggtctttcta gctttgacag taagctggcg Protein function: Negative regulator of the Shh signaling transduction pathway: recruited to primary cilia via association with the IFT complex A (IFT- A) and is required for recruitment of G protein-coupled receptor GPR161 to cilia, a promoter of PKA-dependent basal repression machinery in Shh signaling. Binds to phosphorylated inositide (phosphoinositide) lipids. Both IFT-A- and phosphoinositide-binding properties are required to regulate ciliary G protein-coupled receptor trafficking. Not involved in ciliogenesis. During adipogenesis, regulates ciliary trafficking of FFAR4 in preadipocytes. [The UniProt Consortium]