TTC26 (Vector pUC, Accession No. BC126331)

Length: 1665 Sequence: atgatgcttt caagggccaa acctgctgta ggcagaggcg tacagcacac tgacaaaaga aagaagaaag gtaggaagat tccaaaacta gaggagctac tttcaaaaag agatttcact ggagctatta ccctgttgga gttcaaacgt catgttgggg aagaagaaga ggatactaat ttgtggattg gatattgtgc ctttcacctg ggtgactaca agagagctct ggaggaatac gaaaatgcta caaaagagga aaattgtaat tctgaagtct gggtgaacct agcttgcacc tacttctttc ttgggatgta taaacaagct gaagcagctg gatttaaagc ttcaaaaagc cgactccaaa accgcctcct cttccacttg gctcacaagt ttaatgatga gaaaaaattg atgagctttc atcaaaatct tcaggatgtc acagaagatc aactcagttt ggcctcaatc cactatatgc gatctcacta ccaagaagct atagatatat ataagcgaat actgctagat aacagggaat accttgccct taatgtttat gtggccctct gctactacaa gttggattac tatgatgtgt ctcaagaagt tttggctgtt taccttcagc aaattcctga tagtaccatc gcactcaatc ttaaagcctg taaccatttt cgcctttaca atggcagagc agctgaggca gaactcaaaa gcttgatgga caatgcttct tcatcctttg aatttgctaa agaactcatc aggcacaatc tggttgtttt ccgaggaggt gaaggggctt tgcaggtttt acctccccta gttgatgtca ttcctgaagc taggctaaac ttggtgattt actaccttcg tcaagatgat gtacaagaag cttataactt aattaaggat ctggaaccta ctactcctca ggagtatatt ctcaaaggag tggtcaatgc agcccttggc caggaaatgg gttcaaggga tcatatgaaa attgcccagc agttcttcca gttggtggga ggatcagcta gtgaatgtga tacaatacca gggaggcagt gcatggcttc ctgtttcttc ctgcttaagc aatttgatga tgttttgatt tacctcaact catttaagag ttacttctat aatgatgaca tctttaactt taattatgcc caagccaaag ctgcaacagg caataccagt gagggcgaag aggcgttcct cttgatccaa agtgagaaga tgaaaaatga ttacatttac ctcagctggt tagctcggtg ctatattatg aataagaaac caagactagc ctgggaactt tatcttaaga tggaaacctc cggcgagtcc ttcagtctct tacagctcat tgctaatgac tgctacaaga tgggccagtt ttactattct gccaaagctt ttgatgtcct tgagaggctg gatcctaacc ctgaatattg ggaaggcaaa cggggtgcct gtgtgggcat tttccagatg atcatagctg ggagagaacc caaagagacc cttcgagaag tgctccattt actgagaagc acaggtaaca cccaagtaga atacatgatc cggatcatga agaaatgggc caaagaaaac agagtgtcca Protein function: Component of the intraflagellar transport (IFT) complex B required for transport of proteins in the motile cilium. Required for transport of specific ciliary cargo proteins related to motility, while it is neither required for IFT complex B assembly or motion nor for cilium assembly. Required for efficient coupling between the accumulation of GLI2 and GLI3 at the ciliary tips and their dissociation from the negative regulator SUFU. Plays a key role in maintaining the integrity of the IFT complex B and the proper ciliary localization of the IFT complex B components. Not required for IFT complex A ciliary localization or function. Essential for maintaining proper microtubule organization within the ciliary axoneme. [The UniProt Consortium]