TSPAN33 (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC

Length: 852 Sequence: atggcgcgga gaccccgggc gccggccgcc tccggggagg agttctcctt cgtcagcccg ctggtgaaat acctgctctt cttcttcaac atgctcttct gggtgatttc catggtgatg gtggctgtgg gtgtctacgc tcggctaatg aagcatgcag aagcagccct agcctgcctg gcagtggacc ctgccatcct gctgatcgtg gtgggtgtcc tcatgttcct gctcaccttc tgtggctgca ttgggtccct ccgcgagaac atctgcctcc tgcagacgtt ctccctctgc ctcaccgctg tgttcctgct gcagctggcc gctgggatcc tgggcttcgt cttctcagac aaggctcgag ggaaagtgag tgagatcatc aacaatgcca ttgtgcacta ccgagatgac ttggatctgc agaacctcat tgattttggc cagaaaaagt ttagctgctg tggagggatt tcctacaagg actggtctca gaacatgtat ttcaactgct cagaagacaa ccccagtcga gagcgctgct ctgtgcctta ctcctgttgc ttgcctactc ctgaccaggc agtgatcaac actatgtgtg gccaaggtat gcaggccttt gactacttgg aagctagcaa agtcatctac accaatggct gtattgacaa gttggtcaac tggatacaca gcaacctatt cttacttggt ggtgtggctc taggcctggc catcccccag ctggtgggaa ttctgctgtc ccagatccta gtgaatcaga tcaaagatca gatcaagcta cagctctaca accagcagca ccgggctgac ccatggtact Protein function: Plays an important role in normal erythropoiesis. It has a role in the differentiation of erythroid progenitors. Regulates maturation and trafficking of the transmembrane metalloprotease ADAM10 (PubMed:26686862, PubMed:30463011). Negatively regulates ligand-induced Notch activity probably by regulating ADAM10 activity (PubMed:26686862). Mediates docking of ADAM10 to zonula adherens by interacting with ADAM10 and, in a PDZD11-dependent manner, with the zonula adherens protein PLEKHA7 (PubMed:30463011). [The UniProt Consortium]