TRIM37 (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC,

Length: 2895 Sequence: atggatgaac agagcgtgga gagcattgct gaggttttcc gatgtttcat ttgtatggag aaattgcggg atgcacgcct gtgtcctcat tgctccaaac tgtgttgttt cagctgtatt aggcgctggc tgacagagca gagagctcaa tgtcctcatt gccgtgctcc actccagcta cgagaactag taaattgtcg ttgggcagaa gaagtaacac aacagcttga tactcttcaa ctctgcagtc tcaccaaaca tgaagaaaat gaaaaggaca aatgtgaaaa tcaccatgaa aaacttagtg tattttgctg ggcttgtaag aagtgtatct gccatcagtg tgcactttgg ggaggaatgc atggcggaca tacctttaaa cctttggcag aaatttatga gcaacacgtc actaaagtga atgaagaggt agccaaactt cgtcggcgtc tcatggaact gatcagctta gttcaagaag tggaaaggaa tgtagaagct gtaagaaatg caaaagatga gcgtgttcgg gaaattagga atgcagtgga gatgatgatt gcacggttag acacacagct gaagaataag cttataacac tgatgggtca gaagacatct ctaacccaag aaacagagct tttggaatcc ttacttcagg aggtggagca ccagttgcgg tcttgtagta agagtgagtt gatatctaag agctcagaga tccttatgat gtttcagcaa gttcatcgga agcccatggc atcttttgtt accactcctg ttccaccaga ctttaccagt gaattagtgc catcttacga ttcagctact tttgttttag agaatttcag cactttgcgt cagagagcag atcctgttta cagtccacct cttcaagttt caggactttg ctggaggtta aaagtttacc cagatggaaa tggagttgtg cgaggttact acttatctgt gtttctggag ctctcagctg gcttgcctga aacttctaaa tatgaatatc gtgtagagat ggttcaccag tcctgtaatg atcctacaaa aaatatcatt cgagaatttg catctgactt tgaagttgga gaatgctggg gctataatag atttttccgt ttggacttac tcgcaaatga aggatacttg aatccacaaa atgatacagt gattttaagg tttcaggtac gttcaccaac tttctttcaa aaatcccggg accagcattg gtacattact cagctggaag ctgcacagac tagttatatc caacaaataa acaaccttaa agagagactt actattgagc tgtctcgaac tcagaagtca agagatttgt caccaccaga taaccatctt agcccccaaa atgatgatgc tctggagaca cgagctaaga agtctgcatg ctctgacatg cttctcgaag gtggtcctac tacagcttct gtaagagagg ccaaagagga tgaagaagat gaggagaaga ttcagaatga agattatcat cacgagcttt cagatggaga tctggatctg gatcttgttt atgaggatga agtaaatcag ctcgatggca gcagttcctc tgctagttcc acagcaacaa gtaatacaga agaaaatgat attgatgaag aaactatgtc tggagaaaat gatgtggaat ataacaacat ggaattagaa gagggagaac tcatggaaga tgcagctgct gcaggacccg caggtagtag ccatggttat gtgggttcca gtagtagaat atcaagaaga acacatttat gctccgctgc taccagtagt ttactagaca ttgatccatt aattttaata catttgttgg accttaagga ccggagcagt atagaaaatt tgtggggctt acagcctcgc ccacctgctt cacttctgca gcccacagca tcatattctc gaaaagataa agaccaaagg aagcaacagg caatgtggcg agtgccctct gatttaaaga tgctaaaaag actcaaaact caaatggccg aagttcgatg tatgaaaact gatgtaaaga atacactttc agaaataaaa agcagcagtg ctgcttctgg agacatgcag acaagccttt tttctgctga ccaggcagct ctggctgcat gtggaactga aaactctggc agattgcagg atttgggaat ggaactcctg gcaaagtcat cagttgccaa ttgttacata cgaaactcca caaataagaa gagtaattcg cccaagccag ctcgatccag tgtagcaggt agtctatcac ttcgaagagc agtggaccct ggagaaaata gtcgttcaaa gggagactgt cagactctgt ctgaaggctc cccaggaagc tctcagtctg ggagcaggca cagttctccc cgagccttga tacatggcag tatcggtgat attctgccaa aaactgaaga ccggcagtgt aaagctttgg attcagatgc tgttgtggtt gcagttttca gtggcttgcc tgcggttgag aaaaggagga aaatggtcac cttgggggct aatgctaaag gaggtcatct ggaaggactg cagatgactg atttggaaaa taattctgaa actggagagt tacagcctgt actacctgaa ggagcttcag ctgcccctga agaaggaatg agtagcgaca gtgacattga atgtgacact gagaatgagg agcaggaaga gcataccagt gtgggcgggt ttcacgactc cttcatggtc atgacacagc ccccggatga agatacacat tccagttttc ctgatggtga acaaataggc cctgaagatc tcagcttcaa tacagatgaa aatagtggaa Protein function: E3 ubiquitin-protein ligase required to prevent centriole reduplication (PubMed:15885686, PubMed:23769972). Probably acts by ubiquitinating positive regulators of centriole reduplication (PubMed:23769972). Mediates monoubiquitination of 'Lys-119' of histone H2A (H2AK119Ub), a specific tag for epigenetic transcriptional repression: associates with some Polycomb group (PcG) multiprotein PRC2-like complex and mediates repression of target genes (PubMed:25470042). Has anti-HIV activity (PubMed:24317724). [The UniProt Consortium]