TMEM30B (Vector pUC, Accession No. BC113559)

Length: 1056 Sequence: atgacctgga gcgccacggc ccggggcgcc caccagcccg acaacaccgc cttcactcag cagcgcctcc ccgcctggca gccgctgctg tcggccagca tcgcgctgcc gctcttcttc tgcgcgggcc tggccttcat cggcctgggc ctgggcctct actactcctc caacggcatc aaggagctgg agtacgacta tacaggcgac ccgggcaccg gtaactgctc ggtgtgcgcc gcggctggcc agggccgggc gctgccgccc ccctgctcgt gcgcctggta cttctcgctg cccgagctct tccagggccc agtgtacctc tactacgagc tgaccaactt ctaccagaac aaccggcgct acggcgtgtc ccgcgacgac gcgcagctga gcggactccc cagcgcgctg cgccaccctg tcaacgagtg cgccccctac cagcgcagcg cggccggcct gcccatcgcg ccctgcggcg ccatcgccaa cagcctcttc aacgactcct tctcgctttg gcaccagcgc cagcccggcg ggccctacgt cgaggtgccg ctcgaccgct ccggcatcgc ctggtggacc gactaccacg tcaagttccg caacccgccg ctggtcaacg gcagcctggc gttggccttc cagggcacgg cgcccccgcc caactggcgc cggccagtct acgagctcag ccccgacccc aacaacaccg gcttcatcaa tcaggacttc gtggtgtgga tgcgcacggc ggcgctgccc acgttccgca aactgtacgc gcgcatccgc cagggcaact actcggccgg gctgccgcgg ggcgcctacc gcgtcaacat cacctacaac tacccggtgc gcgcgttcgg cggccacaag ctcctcatct tcagcagcat ctcgtggatg ggtggcaaga accccttcct gggcatcgcc tacctggtcg tcggctccct ctgcatcctc accggctttg tcatgctggt cgtctacatt cgctaccagg accaggacga cgacgacgag Protein function: Accessory component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. The beta subunit may assist in binding of the phospholipid substrate (Probable). Can mediate the export of alpha subunits ATP8A1, ATP8B1, ATP8B2 and ATP8B4 from the ER to the plasma membrane. [The UniProt Consortium]