TIMM8A (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC,

Length: 219 Sequence: atgctcctga atgacaagtg ggtcaatgaa gaaattaaaa agaaaattga aaaatgtctt gaaacaaatg ataatggaaa cacaacatac caaaacctat gggatacagc aaaagcagta gtgagaggga agtttatagc tataagcacc tacatcaaaa aagaagaaaa acttcaaata aataatctaa ccatgaatct tatagaacta Protein function: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. The TIMM8- TIMM13 complex mediates the import of proteins such as TIMM23, SLC25A12/ARALAR1 and SLC25A13/ARALAR2, while the predominant TIMM9- TIMM10 70 kDa complex mediates the import of much more proteins. Probably necessary for normal neurologic development. [The UniProt Consortium]