TFDP2 (Vector pENTR223.1, Accession No. BC021113)

Length: 1161 Sequence: atgattataa gcacaccaca gagactaacc agttcaggaa gtgttctgat tgggagtcca tatacccctg caccagcaat ggttactcag acacacatag cagaagctac tggctgggtc cctggtgata gaaaacgggc tagaaaattt atagactctg atttttcaga aagtaaacga agcaaaaaag gagataaaaa tgggaaaggc ttgagacact tttcaatgaa agtgtgtgag aaagttcaac gaaaaggtac aacatcgtac aatgaagtcg ctgatgagct ggtgtcagag ttcaccaatt caaataacca tttggctgct gattcgcagg cttatgatca gaagaacatt aggcgaagag tttatgatgc tttaaatgtg ctaatggcaa tgaacataat ttcaaaggaa aaaaaagaaa tcaagtggat tggcctgcct accaattctg ctcaggaatg tcagaatctg gagatagaga agcagaggcg gatagaacgg ataaagcaga agcgggccca gctgcaagaa cttctcctac agcaaatcgc tttcaaaaac ctggtacaga gaaatcgaca aaatgagcag caaaaccagg gcccgccggc tctgaactct accattcagc tgccattcat aatcatcaat acaagcagaa aaacagtcat agattgcagc atctccagtg acaagtttga gtatcttttc aattttgaca acacctttga gatccatgat gacatagaag tactaaagcg gatgggaatg tcgtttggcc tggagtcagg caaatgctct ctggaggatc tgaaacttgc gaaatccctg gtgccaaagg ctttagaagg ttatatcaca gatatctcca caggaccttc ttggttaaat cagggactac ttctgaactc tacccaatca gtttcaaatt tagacctgac cactggtgcc accttacccc agtcaagtgt aaaccaaggg ttatgcttgg atgcagaagt ggccttagca actgggcagt tcctggcccc aaacagtcac cagtccagca gtgcggcctc tcactgctcc gagtcccgag gcgagacccc ctgttcgttc aatgatgaag atgaggaaga tgatgaggag gattcctcct ccccagaata Protein function: Can stimulate E2F-dependent transcription. Binds DNA cooperatively with E2F family members through the E2 recognition site, 5'-TTTC[CG]CGC-3', found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The TFDP2:E2F complex functions in the control of cell- cycle progression from G1 to S phase. The E2F1:DP complex appears to mediate both cell proliferation and apoptosis. Blocks adipocyte differentiation by repressing CEBPA binding to its target gene promoters (PubMed:20176812). [The UniProt Consortium]