TBX6 (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC, A

Length: 1311 Sequence: atgtaccatc cacgagaatt gtacccgtcc ctgggggccg gctaccgcct ggggcccgcc caacctgggg ccgactccag cttcccaccc gccctagcgg agggctaccg ctaccccgaa ctggacaccc ctaaactgga ttgcttcctc tccgggatgg aggctgctcc ccgcaccctg gccgcgcacc cacctctgcc ccttctgccc cctgccatgg gcactgagcc ggccccatca gctccagagg ccctccattc cctcccgggg gtcagcctga gcctggagaa ccgggagcta tggaaggagt tcagctctgt gggaacagaa atgatcatca ccaaagctgg gaggcgcatg ttccctgcct gccgagtgtc agtcactggc ctggaccccg aggcccgcta cttgtttctt ctggatgtga ttccggtgga tggggctcgc taccgctggc agggccggcg ctgggagccc agcggcaagg cagagccccg cctgcctgac cgtgtctaca ttcaccccga ctctcctgcc actggtgcac attggatgcg gcagcctgtg tctttccatc gtgtcaagct caccaacagc acgctggacc cccacggcca cctgatcctg cactccatgc acaagtacca accccgcata cacctagttc gggcagccca gctctgcagc cagcactggg ggggcatggc ctccttccgc ttccccgaga ccacattcat ctccgtgaca gcctaccaga acccacagat cacacaactg aagattgcag ccaatccctt tgccaaaggc ttccgggaga acggcagaaa ctgtaagagg gagcgagacg cccgtgtgaa gaggaaactg cggggcccag agccagcagc cacagaggcc tatgggagcg gagacacacc aggtggtccc tgcgactcca ccctgggtgg agacattcgt gaatcagatc cagaacaggc cccagccccc ggggaagcca ccgctgcccc ggcacctctg tgtggtggcc ccagtgctga ggcctacctc ctgcaccctg cggctttcca tggggccccc agtcaccttc ccaccaggag ccccagcttc ccggaggctc cagactccgg gcgctcagcc ccctactcgg ctgcatttct ggagctgccg cacgggtcag ggggctccgg gtacccagcg gctccaccgg cggtaccctt tgccccgcac tttctccaag ggggcccctt ccctctacca tacaccgcgc ctgggggcta tctggatgtg ggctccaaac ccatgtactg Protein function: T-box transcription factor that plays an essential role in the determination of the fate of axial stem cells: neural vs mesodermal. Acts in part by down-regulating, a specific enhancer (N1) of SOX2, to inhibit neural development. Seems to play also an essential role in left/right axis determination and acts through effects on Notch signaling around the node as well as through an effect on the morphology and motility of the nodal cilia. [The UniProt Consortium]