TAOK3 (Vector pUC, Accession No. BC002756)

Length: 2697 Sequence: atgcgtaaag gggtgctgaa ggacccagag attgccgatc tattctacaa agatgatcct gaggaacttt ttattggttt gcatgaaatt ggacatggaa gttttggagc agtttatttt gctacaaatg ctcacaccag tgaggtggtg gcaattaaga agatgtccta tagtgggaag cagacccatg agaaatggca agatattctt aaggaagtta aatttttacg acaattgaag catcctaata ctattgagta caaaggctgt tacttgaaag aacacactgc ttggttggtg atggaatatt gcttaggctc agcctctgat ttattagaag ttcataaaaa accacttcag gaagtggaga tcgctgccat tactcatgga gccttgcatg gactagccta cctacattct catgcattga ttcataggga tattaaagca ggaaatattc ttctaacaga gccaggtcag gtaaaactag ctgattttgg atctgcttca atggcttctc ctgccaactc cttcgtgggc acaccttact ggatggctcc agaggtgatc ttagctatgg atgaaggaca gtatgatggg aaagttgata tttggtcact tggcatcact tgtattgaat tggcggaacg gaagccgccc cttttcaaca tgaatgcaat gagtgcctta tatcacattg cccagaatga ctccccaacg ttacagtcta atgaatggac agactccttt aggagatttg ttgattactg cttgcagaaa atacctcagg aaaggccaac atcagcagaa ctattaaggc atgactttgt tcgacgagac cggccactac gtgtcctcat tgacctcata cagaggacaa aagatgcagt tcgtgagcta gataacctac agtaccgaaa aatgaaaaaa atacttttcc aagagacacg gaatggaccc ttgaatgagt cacaggagga tgaggaagac agtgaacatg gaaccagcct gaacagggaa atggacagcc tgggcagcaa ccattccatt ccaagcatgt ccgtgagcac aggcagccag agcagcagtg tgaacagcat gcaggaagtc atggacgaga gcagttccga acttgtcatg atgcacgatg acgaaagcac aatcaattcc agctcctccg tcgtgcataa gaaagatcat gtattcataa gggatgaggc gggccacggc gatcccaggc ctgagccgcg gcctacccag tcagttcaga gccaggccct ccactaccgg aacagagagc gctttgccac gatcaaatca gcatctttgg ttacacgaca gatccatgag catgagcagg agaacgagtt gcgggaacag atgtcaggtt ataagcggat gcggcgccag caccagaagc agctgatcgc cctggagaac aagctgaagg ctgagatgga cgagcaccgc ctcaagctac agaaggaggt ggagacgcat gccaacaact cgtccatcga gctggagaag ctggccaaga agcaagtggc tatcatagaa aaggaggcaa aggtagctgc agcagatgag aagaagttcc agcaacagat cttggcccag cagaagaaag atttgacaac tttcttagaa agtcagaaga agcagtataa gatttgtaag gaaaaaataa aagaggaaat gaatgaggac catagcacac ccaagaaaga gaagcaagag cggatctcca aacataaaga gaacttgcag cacacacagg ctgaagagga agcccacctt ctcactcaac agagactgta ctacgacaaa aattgtcgtt tcttcaagcg gaaaataatg atcaagcggc acgaggtgga gcagcagaac attcgggagg aactaaataa aaagaggacc cagaaggaga tggagcatgc catgctaatc cggcacgacg agtccacccg agagctagag tacaggcagc tgcacacgtt acagaagcta cgcatggatc tgatccgttt acagcaccag acggaactgg aaaaccagct ggagtacaat aagaggcgag aaagagaact gcacagaaag catgtcatgg aacttcggca acagccaaaa aacttaaagg ccatggaaat gcaaattaaa aaacagtttc aggacacttg caaagtacag accaaacagt ataaagcact caagaatcac cagttggaag ttactccaaa gaatgagcac aaaacaatct taaagacact gaaagatgag cagacaagaa aacttgccat tttggcagag cagtatgaac agagtataaa tgaaatgatg gcctctcaag cgttacggct agatgaggct caagaagcag aatgccaggc cttgaggcta cagctccagc aggaaatgga gctgctcaac gcctaccaga gcaaaatcaa gatgcaaaca gaggcacaac atgaacgtga gctccagaag ctagagcaga gagtgtctct gcgcagagca caccttgagc agaagattga agaggagctg gctgcccttc agaaggaacg cagcgagaga ataaagaacc tattggaaag gcaagagcga gagattgaaa cttttgacat ggagagcctc agaatgggat ttgggaattt ggttacatta gattttccta aggaggacta Protein function: Serine/threonine-protein kinase that acts as a regulator of the p38/MAPK14 stress-activated MAPK cascade and of the MAPK8/JNK cascade. Acts as an activator of the p38/MAPK14 stress-activated MAPK cascade. In response to DNA damage, involved in the G2/M transition DNA damage checkpoint by activating the p38/MAPK14 stress-activated MAPK cascade, probably by mediating phosphorylation of upstream MAP2K3 and MAP2K6 kinases. Inhibits basal activity of MAPK8/JNK cascade and diminishes its activation in response epidermal growth factor (EGF). [The UniProt Consortium]