STT3A (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC,

Length: 2118 Sequence: atgactaagt ttggattttt gcgattgtcc tatgagaagc aggacacact tttgaagctt ctcattctgt caatggctgc tgtattatcc ttctccactc gtctgtttgc tgtcctgaga tttgaaagtg ttatccatga gtttgatccg tactttaatt atcggactac caggttcctg gctgaggagg ggttttataa attccataac tggtttgatg accgagcctg gtaccctttg ggacgaatca ttggaggaac aatttaccca ggtttaatga tcacctctgc tgcaatctac catgtactcc attttttcca catcaccatc gacattcgga atgtctgtgt gttcctggcc cctctcttct cctccttcac caccatcgtc acgtaccacc ttaccaaaga gctcaaggat gcaggggctg ggcttcttgc tgctgccatg attgctgtag ttcctggata tatctcccga tctgtggctg gctcctatga taatgaaggg attgccatct tttgcatgct actcacctac tacatgtgga tcaaggcagt aaagactggt tccatctgtt gggcagctaa gtgtgccctt gcttatttct acatggtctc gtcatgggga ggttatgtgt tcctgatcaa cttaattcct ctccacgtcc tcgtgctgat gctcacaggc cgtttctctc accggatcta tgtggcctac tgtactgttt actgcctggg cactatactt tctatgcaga tctcctttgt gggtttccag cctgtccttt catcagagca catggcagcc tttggggtct ttggtctctg ccagatccat gcctttgtgg attacctgcg cagcaagttg aatccacaac aatttgaagt tcttttccgg agcgtcatct ctctggtagg ctttgtcctt ctcaccgtgg gagctctcct catgctgaca ggaaaaatat ctccctggac ggggcgtttc tactcgctgc tggatccctc ttatgctaag aacaacatcc ccatcattgc ttctgtgtct gagcatcagc ccacaacctg gtcctcatac tattttgacc tgcagctcct cgtcttcatg tttccagttg gcctctatta ctgctttagc aacctgtctg atgcccggat ttttatcatc atgtatggtg tgaccagcat gtacttttca gctgtaatgg tgcgtctaat gctagtgttg gcacctgtta tgtgcattct ctctggcatt ggagtctccc aggtgctgtc cacatacatg aagaatctgg acataagtcg tccagacaag aagagcaaga agcaacagga ttccacctac cctattaaga atgaagtggc aagtgggatg atactggtca tggctttctt tctcatcacc tacacctttc attcaacctg ggtgaccagt gaggcctact cttctccgtc cattgtacta tctgcccgtg gtggggatgg cagtaggatc atatttgatg acttccgaga agcatattat tggcttcgtc ataatactcc agaggatgcg aaggtcatgt cctggtggga ttatggctat cagattacag ctatggcaaa ccgaacaatt ttagtggaca ataacacatg gaataatacc catatttctc gagtagggca ggcaatggcg tccacagagg aaaaagccta tgagatcatg agggagctcg atgtcagcta tgtgctggtc atttttggag gcctcactgg gtattcctct gatgatatca acaagtttct ttggatggtc cggattggag ggagcacaga tacaggcaaa catatcaagg agaatgacta ttatactcca actggggagt tccgtgtgga ccgtgaaggt tctccagtgc tgctcaactg cctcatgtac aagatgtgtt actatcgctt tggacaggtt tacacagaag ccaagcgtcc tccaggcttt gaccgtgtcc gaaatgctga gattgggaat aaagactttg agcttgatgt cctggaggaa gcatatacca cagaacattg gctggtcagg atatacaagg taaaggacct ggataatcga ggcttgtcaa Protein function: Catalytic subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity. This subunit contains the active site and the acceptor peptide and donor lipid-linked oligosaccharide (LLO) binding pockets. STT3A is present in the majority of OST complexes and mediates cotranslational N-glycosylation of most sites on target proteins, while STT3B-containing complexes are required for efficient post-translational glycosylation and mediate glycosylation of sites that have been skipped by STT3A (PubMed:19167329). [The UniProt Consortium]