ST3GAL5 (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC

Length: 1173 Sequence: atgccaagtg agtacaccta tgtgaaactg agaagtgatt gctcgaggcc ttccctgcaa tggtacaccc gagctcaaag caagatgaga aggcccagct tgttattaaa agacatcctc aaatgtacat tgcttgtgtt tggagtgtgg atcctttata tcctcaagtt aaattatact actgaagaat gtgacatgaa aaaaatgcat tatgtggacc ctgaccgtgt aaagagagct cagaaatatg ctcagcaagt cttgcagaag gaatgtcgtc ccaagtttgc caagacatca atggcgctgt tatttgagca caggtatagc gtggacttac tcccttttgt gcagaaggcc cccaaagaca gtgaagctga gtccaagtac gatcctcctt ttgggttccg gaagttctcc agtaaagtcc agaccctctt ggaactcttg ccagagcacg acctccctga acacttgaaa gccaagacct gtcggcgctg tgtggttatt ggaagcggag gaatactgca cggattagaa ctgggccaca ccctgaacca gttcgatgtt gtgataaggt taaacagtgc accagttgag ggatattcag aacatgttgg aaataaaact actataagga tgacttatcc agagggcgca ccactgtctg accttgaata ttattccaat gacttatttg ttgctgtttt atttaagagt gttgatttca actggcttca agcaatggta aaaaaggaaa ccctgccatt ctgggtacga ctcttctttt ggaagcaggt ggcagaaaaa atcccactgc agccaaaaca tttcaggatt ttgaatccag ttatcatcaa agagactgcc tttgacatcc ttcagtactc agagcctcag tcaaggttct ggggccgaga taagaacgtc cccacaatcg gtgtcattgc cgttgtctta gccacacatc tgtgcgatga agtcagtttg gcgggttttg gatatgacct caatcaaccc agaacacctt tgcactactt cgacagtcaa tgcatggctg ctatgaactt tcagaccatg cataatgtga caacggaaac caagttcctc ttaaagctgg tcaaagaggg agtggtgaaa gatctcagtg gaggcattga tcgtgaattt Protein function: Transfers the sialyl group (N-acetyl-alpha-neuraminyl or NeuAc) from CMP-NeuAc to the non-reducing terminal galactose (Gal) of glycosphingolipids forming gangliosides (important molecules involved in the regulation of multiple cellular processes, including cell proliferation and differentiation, apoptosis, embryogenesis, development, and oncogenesis) (PubMed:9822625, PubMed:16934889). Mainly involved in the biosynthesis of ganglioside GM3 but can also use different glycolipids as substrate acceptors such as D- galactosylceramide (GalCer), asialo-GM2 (GA2) and asialo-GM1 (GA1), although less preferentially than beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)- Cer (LacCer) (PubMed:16934889). [The UniProt Consortium]