SSBP1 (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC,

SSBP1 (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC,
Item number Size Datasheet Manual SDS Delivery time Quantity Price
CSB-CL022706HU.10 10 µg - - -

10 - 14 business days*

176.00€
 
Length: 447 Sequence: atgtttcgaa gacctgtatt acaggtactt cgtcagtttg taagacatga gtccgaaaca... more
Product information "SSBP1 (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC,"
Length: 447 Sequence: atgtttcgaa gacctgtatt acaggtactt cgtcagtttg taagacatga gtccgaaaca actaccagtt tggttcttga aagatccctg aatcgtgtgc acttacttgg gcgagtgggt caggaccctg tcttgagaca ggtggaagga aaaaatccag tcacaatatt ttctctagca actaatgaga tgtggcgatc aggggatagt gaagtttacc aactgggtga tgtcagtcaa aagacaacat ggcacagaat atcagtattc cggccaggcc tcagagacgt ggcatatcaa tatgtgaaaa aggggtctcg aatttatttg gaagggaaaa tagactatgg tgaatacatg gataaaaata atgtgaggcg acaagcaaca acaatcatag ctgataatat tatatttctg agtgaccaga cgaaagagaa Protein function: Binds preferentially and cooperatively to pyrimidine rich single-stranded DNA (ss-DNA) (PubMed:21953457, PubMed:23290262). In vitro, required to maintain the copy number of mitochondrial DNA (mtDNA) and plays crucial roles during mtDNA replication that stimulate activity of the replisome components POLG and TWNK at the replication fork (PubMed:21953457, PubMed:12975372, PubMed:26446790, PubMed:15167897). Promotes the activity of the gamma complex polymerase POLG, largely by organizing the template DNA and eliminating secondary structures to favor ss-DNA conformations that facilitate POLG activity (PubMed:26446790, PubMed:21953457). In addition it is able to promote the 5'-3' unwinding activity of the mtDNA helicase TWNK (PubMed:12975372). May also function in mtDNA repair (PubMed:23290262). [The UniProt Consortium]
Keywords: SSBP, SSBP1, MtSSB, Mt-SSB, PWP1-interacting protein 17, Single-stranded DNA-binding protein, mitochondrial
Supplier: Cusabio
Supplier-Nr: CL022706HU

Properties

Application: Molecular biology, clone
Species reactivity: human

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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