SPC25 (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC,

Length: 675 Sequence: atggtagagg acgaactggc acttttcgat aaaagcataa atgaattttg gaataaattc aaaagtacgg acacctcctg tcagatggcg ggactaagag atacctacaa ggattccatc aaagcatttg cagaaaagct gtctgtgaaa ttaaaggaag aagaacgaat ggttgagatg tttctggaat atcaaaatca gatcagcagg caaaataagc tcattcaaga aaaaaaggat aacttgttaa aattgattgc tgaagtaaaa ggcaaaaagc aggaattgga agtactgact gcaaatatcc aggatcttaa ggaagaatat tctaggaaga aggaaactat ttctactgct aataaagcga atgcagagag gttgaaaagg ctgcagaaat ctgcagactt gtataaagat cgacttggac tagaaattcg aaaaatttat ggtgagaaat tgcagtttat tttcactaat attgacccta agaatcctga gagcccattt atgttttcct tacatctcaa tgaagcaagg gactatgaag tgtcagatag tgcccctcat cttgagggcc tagcagaatt tcaagagaat gtaaggaaga ccaacaattt ttcagctttt cttgccaatg ttcggaaagc ttttactgcc acggtttata Protein function: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity (PubMed:14699129, PubMed:14738735). Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore (PubMed:14738735, PubMed:14699129). The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules (PubMed:23085020). [The UniProt Consortium]